Problem using Trend Micro OfficeScan antivirus software with MassLynx - WKB12352

SYMPTOMS

• Problems include:
• Cannot open the MassLynx inlet editor
• Run samples pane freezes when Start pressed "not responding" error message
• Communications losses with MassLynx

ENVIRONMENT

• MassLynx
• Trend Micro antivirus software 
• Trend Micro Apex One Security Agent

CAUSE

Incompatibility between (unsupported antivirus software) Trend Micro configuration and MassLynx

FIX or WORKAROUND

In Trend Micro disable the following:

Application Control

Behavior Monitoring

Data Loss Prevention

Device Control

Endpoint Sensor

Firewall

Outbreak Prevention Policy

Predictive Machine Learning

Suspicious Connection Service

Vulnerability Protection

Consider disabling SmartScan

ADDITIONAL INFORMATION

Trend Micro was initially configured to not scan the C:\MassLynx and C:\Program Files (X86)\Waters Instruments folders, but this did not solve the problem with the inlet editor.