What formulas does Empower use to calculate relative resolution for System Suitability? - WKB52882
Article number: 52882
ENVIRONMENT
- Empower 3
- System Suitability
- Regional pharmacopeia
ANSWER
The formulas are described in the Empower System Suitability Quick Reference Guide (71500031605), which can be downloaded from the Waters website. See section 3.6 for details.
The specific resolution equation used to calculate relative resolution depends on your Pharmacopeia choice on the System Suitability tab of the Processing Method window. The four Pharmacopeia options are US Pharmacopeia (USP), European Pharmacopeia (EP), Japanese Pharmacopeia (JP), and "All".
- Selecting "All" calculates relative resolution using peak widths at baseline between tangent lines (Figure 3.16)
- Selecting USP, EP, or JP calculates relative resolution using peak widths at half height (Figures 3.17 and 3.18)
ADDITIONAL INFORMATION
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