How is the Impurity RRF field on the Components tab in the processing method within Empower used? - WKB14718

ENVIRONMENT

• Empower 3 Feature Release 3 (FR3)

ANSWER

Impurity RRF is a field on the Components table of the processing method. Impurity RRF was added to allow correction of the area of impurities. The main formula it uses is the following:

Corrected Area = Area * Impurity RRF 

Corrected Area is used to calculate other fields based on the selected Impurity Response on the Impurity tab of the processing method. The following are examples of the next formulas used:

% Area = Area / Total Area * 100 
% Adjusted Area = Corrected Area~ / Adjusted Total Area * 100 
% Area Against Main Component = Corrected Area~ / Area of Main Component * 100 
% w/w where (w=Area) = Area / Area of Main Component * 100 

These were introduced in E3 FR2. However, some important improvements were made in E3 SR2 to include the  %w/w calculation where Value of w is Height or Corrected Area:

If w Value = Corrected Area~, the formula for %w/w is as follows: 
%w/w = (Corrected Area~ of this peak / Corrected Area~ of Impurity Main Component peak) * 100. 

If w Value = Area, the formula for %w/w is as follows: 
%w/w = (Area of this peak / Area of Impurity Main Component peak) * 100. 

If w Value = Height, the formula for %w/w is as follows: 
%w/w = (Height of this peak * Impurity RRF) / Height of Impurity Main Component peak) * 100. 

Also, with the addition of Corrected Area~, % Area against Main Component is now calculated as follows: 
% Area against Main Component = (Corrected Area~ of this peak / Area of Impurity Main Component peak) * 100. 

ADDITIONAL INFORMATION