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What does "residual volume" mean when referring to autosampler vials? - WKB1647

Article number: 1647


  • HPLC Autosamplers (715, 717, Alliance, 2695, 2795)
  • ACQUITY UPLC Sample Managers


  • The syringe needle of an autosampler does not go all the way to the bottom of a vial, and therefore some sample will always remain. This is referred to as the residual volume of the vial. Some vials have a tapered bottom for example, which decreases the residual volume.  This can be important if the sample is valuable and of limited amount.

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