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What does "residual volume" mean when referring to autosampler vials? - WKB1647

Article number: 1647

ENVIRONMENT

  • HPLC Autosamplers (715, 717, Alliance, 2695, 2795)
  • ACQUITY UPLC Sample Managers

ANSWER

The syringe needle of an autosampler does not go all the way to the bottom of a vial, so some sample always remains. This is referred to as the "residual volume" of the vial. Some vials have a tapered bottom, which decreases the residual volume. This can be important if the sample is valuable or if only a small amount is available.

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