What is the best way to switch solvent from THF to DMF on ACQUITY APC XT columns? - WKB81356
Article number: 81356
ENVIRONMENT
- Column care and use
- Solvent changing
- Advanced polymer chromatography (APC)
- ACQUITY APC XT
ANSWER
The pore size, flow rate, and viscosity restrictions must be considered when doing the solvent switch.
ADDITIONAL INFORMATION
DMF has a higher viscosity than THF.
The DMF at 20 and 40 °C has a viscosity greater than 0.6 cP, so the flow rate ranges listed in the care and use manual must be observed to avoid damaging the columns.
For additional information, see the ACQUITY APC Columns Care and Use Manual and Can I clean my ACQUITY APC column in reverse direction?
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