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Can I clean XBridge BEH SEC columns and ACQUITY UPLC BEH SEC Columns with injections of DMSO (dimethylsulfoxide)? - WKB50971

Article number: 50971

ENVIRONMENT

  • XBridge BEH SEC Columns
  • ACQUITY UPLC BEH SEC Columns
  • Column Cleaning

ANSWER

Yes. See details in "additional information" section below.

ADDITIONAL INFORMATION

If cleaning the column with DMSO, the recommended cleaning injection solution should be 50:50 DMSO:H2O in a sample vial. 

Then, run 100% H2O as the mobile phase and make 5 to 10 injections of the 50:50 DMSO:H2O solution as the cleaning solution.

The Care & Use Manuals provide other cleaning suggestions:

ACQUITY UPLC®  BEH SEC Columns  and Standards Care & Use Manual (lit code 720003385en): https://help.waters.com/help/en/support/library-details.html?documentid=720003385en

XBridge Protein BEH SEC Columns & Standards Care & Use Manual (lit code 720005206en): https://help.waters.com/help/en/support/library-details.html?documentid=720005206en

 

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