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Waters

HDX gives no peaks for either pre-digest or intact PhosB - WKB80210

Article number: 80210

SYMPTOMS

  • No sample signal peaks seen for pre-digest or intact PhosB
  • No leak on injection port
  • Trapping method starts correctly
  • Syringe picks up sample and transfers correctly

ENVIRONMENT

  • HDX
  • HDX2

CAUSE

Damaged pepsin column is digesting incorrectly and adsorbing predigested sample.

FIX or WORKAROUND

Replace the pepsin column.

ADDITIONAL INFORMATION

 

id80210, LEAPPAL, LEAPPAL3, UPNHDXMGR

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