What is the "MSe acquisition method" on a QTof? - WKB84530

ENVIRONMENT

• SYNAPT G2
• SYNAPT G2-S
• SYNAPT G2-Si
• Vion IMS QTof
• Xevo G2 QTof
• Xevo G2 Tof
• Xevo G2-S
• Xevo G2-XS

ANSWER

MSe is a novel mode of data acquisition that permits the seamless collection of a comprehensive catalog of information for both the precursor and fragment ions in a single analysis. This is achieved by rapidly alternating between two functions. The first, acquired at low energy, provides exact mass precursor ion spectra. The second, at elevated energy, provides high-energy exact mass of the fragment ions. In addition to providing increased confidence in identification, fragmentation can help differentiate between isobaric compounds.

ADDITIONAL INFORMATION

See the attached PDF for more information.

An Overview of the Principles of MSE The Engine that Drives MS Performance.pdf