Low sensitivity only on the sample probe of a Xevo G2 XS QTof - WKB7084

SYMPTOMS

• The counts for the same sample are 10x higher on the LockSpray probe than on the sample probe.
• Switching the fluidics line for the sample and LockSpray does not improve the sample probe counts.

ENVIRONMENT

Xevo G2 XS QTof

CAUSE

The probe position is not optimal. 

FIX or WORKAROUND

1. While infusing a sample through the sample probe and monitoring the counts on the tune page, adjust the probe position using the silver micrometer to the left of the sample probe (left arrow in the picture).

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2. Adjust the capillary position for optimal counts using the black ridged collar at the top of the sample probe (top right arrow in the picture). This should tune so that only 0.5 to 1 mm is protruding from the end of the probe tip. 

ADDITIONAL INFORMATION