- Unstable chromatographic peaks (response sometimes drops to baseline; jagged peaks)
- ACQUITY QDa Detector
The MS instrument method sampling rate is too high to allow appropriate chromatographic peak characterization.
FIX or WORKAROUND
- Set the sampling rate appropriately for the experiment (typically, lower it) to ensure that enough points per peak can be sampled. See the Actual vs. Intended sampling rate feedback in the MS instrument method for guidance.