Negative drops in baseline and random pressure fluctuations during GPC with 2695 Alliance and RI - WKB70936
Article number: 70936
SYMPTOMS
- Negative drops in baseline
- During run, random pressure fluctuations that do not correspond to negative drops
- Recent system PM
- Degasser chambers and pump recently replaced
ENVIRONMENT
- Alliance HPLC System
- 2695 Separations Module
- 2410 Differential Refractometer
- 2414 Refractive Index Detector
CAUSE
Partial clog in tubing from dirty solvents
FIX or WORKAROUND
- Replace tubing from column to detector and any tubing joining columns together.
- Inspect solvent bottles and make sure that there are no visible particulates in the bottles.
- If there are particulates, replace or thoroughly clean the bottles.
- Replace solvent filters.
ADDITIONAL INFORMATION
id70936, 2410, 2414, 2414B, 2690, 2690D, 2690DUPGD, 2690UP, 2695, 2695D, 2695DE, 2695DEB, 2695DUP, 2695E, 2695EB, 2695INERT, 2695UP, A-10RI, A-10SSM, ALLCOLCLR, ALLCOLHTR, ALLCOLHTRB, EMPGPC, GPCV2K, pressure ripple