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ACQUITY H-Class QSM retention time shifts after system prime - WKB58099

Article number: 58099

SYMPTOMS

  • Retention time initially shifts to a longer retention time than expected after refreshing solvents and repriming the pump.
  • Retention time gradually reverts back to expected retention time after several days and then remains constant until the solvents are refreshed again.

ENVIRONMENT

  • ACQUITY UPLC H-Class

CAUSE

Air within pump

FIX or WORKAROUND

Prime all lines with IPA or methanol for 3 minutes, and then reprime with mobile phases.

ADDITIONAL INFORMATION

 

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