How to perform the ACQUITY UPLC BSM and QSM dynamic leak test - WKB46882

OBJECTIVE or GOAL

Perform the dynamic leak test for ACQUITY BSM, QSM, and ISM pumps.

ENVIRONMENT

• ACQUITY UPLC I-Class Binary Solvent Manager (BSM)
• ACQUITY UPLC BSM (Firmware 1.50 or higher)
• ACQUITY APC
• ACQUITY APC Isocratic Solvent Manager
• ACQUITY Arc
• ACQUITY Arc Premier
• ACQUITY UPLC
• ACQUITY UPLC H-Class
• ACQUITY UPLC H-Class Bio
• ACQUITY UPLC H-Class Quaternary Solvent Manager (QSM)
• ACQUITY UPLC I-Class
• ACQUITY UPLC H-Class PLUS
• ACQUITY UPLC H-Class PLUS Bio
• ACQUITY UPLC I-Class PLUS
• ACQUITY UPLC M-Class
• nanoACQUITY UPLC
• ACQUITY Premier System
• MassLynx
• Empower 3
• UNIFI
• waters_connect

PROCEDURE

NOTE: Before performing the test, it is reccommended that the pump head seals are "exercised" for 30 minutes by preparing the system to achieve a system pressure typically used for the methods run - for example, 10,000 psi. 

1. Ensure that the solvent line is fully submerged in solvent in the solvent reservoir.
2. Open ACQUITY Console.
3. Select the BSM/QSM/ISM from the system tree on the left-hand side of the screen (expand the system tree by clicking the "+" sign if needed).
4. Select "Maintain" from along the top of the window (see Additional Information below)
5. Select "Leak Test" or "Dynamic Leak Test" if available.
6. Keep the default pressure for accumulator and primary unchanged (14000 psi) and choose endpoint = Vent Valve.
7. Select the appropriate pump (if BSM, this will be A or B), solvent line, vent valve position, check Prime and then click "Start".
8. The Pump will Prime for 2 minutes then the test runs. Test results will show after the test is completed.
9. Repeat for Pump B [if it is a Binary Solvent Manager (BSM)].
10. If the test fails, ensure the solvent lines are filled with mobile phase via visual inspection, prime the solvent lines again and run the leak test once more.
11. The tests on Step-8 and Step-10 would test the Pumps' condition up to the point of Vent Valve. 
12. Remove the column and attach a Union (700002637) plugged with High Pressure pin (700002747) to the active preheater (or column inlet tubing).
    Note: Tighten the pin plug towards the column inlet tubing a little more than finger-tight to make sure it's leak free.
    
    
13. Repeat the Dynamic Leak Test with endpoint column selected (Needle and Seal not included).
    Note: Either the A or B side can be used to do that test.
14. Finally, repeat the Dynamic Leak Test with endpoint column selected (Needle and Seal included).

ADDITIONAL INFORMATION

Within ACQUITY console (for MassLynx and Empower)

Within UNIFI or waters_connect

VIDEO on Waters.com How to perform a QSM-R leak test

diagnostics_-qsm-r-leak-test.mp4