Peak splitting observed on an ACQUITY H-Class - WKB30746
Article number: 30746
SYMPTOMS
- Peak split into three
- No issue observed when making smaller injections
- Replacing the extension loop does not resolve the issue
ENVIRONMENT
- ACQUITY H-Class
- ACQUITY UPLC Evaporative Light Scattering Detector (ELSD)
- 50-µL extension loop
CAUSE
Drift tube dirty or flooded
FIX or WORKAROUND
Clean the drift tube as described in the ACQUITY UPLC Evaporative Light Scattering Detector Getting Started Guide (71500109303).