Peak splitting observed on an ACQUITY H-Class - WKB30746
Article number: 30746
SYMPTOMS
- Peak split into three
- No issue observed when making smaller injections
- Replacing the extension loop does not resolve the issue
ENVIRONMENT
- ACQUITY H-Class
- ACQUITY UPLC Evaporative Light Scattering Detector (ELSD)
- 50-µL extension loop
CAUSE
Drift tube dirty or flooded
FIX or WORKAROUND
Clean the drift tube as described in the ACQUITY UPLC Evaporative Light Scattering Detector Getting Started Guide (71500109303).
ADDITIONAL INFORMATION
How to clean an ACQUITY UPLC ELS Detector - WKB230245
id30746, UPBINARY, UPELS, UPELSARC, UPQSM, UPQSM+, UPQSMBIO, UPQSMBIO+, UPSMFTN, UPSMFTN+, UPSMFTNB+, UPSMFTNBIO