ELS Detector gives poor signal or flat-line data - WKB297874
Article number: 297874
SYMPTOMS
- ELSD signal is flat
- ELSD signal is inconsistent
ENVIRONMENT
- ACQUITY UPLC ELS Detector
- 2424 Evaporative Light Scattering Detector
- 2420 Evaporative Light Scattering Detector
CAUSE
Dry drain tubing leaves ELSD drift chamber unsealed. There must be liquid draining or else the signal will not be stable.
FIX or WORKAROUND
Use a syringe or water bottle to add water or other liquid to the J drain tubing below the nebulizer.
ADDITIONAL INFORMATION