UPLC high pressure - WKB246270

SYMPTOMS

• System high pressure increases until overpressure occurs
• High pressure remains when disconnecting column
• Pressure decreases when disconnecting APH from injection valve

ENVIRONMENT

• ACQUITY UPLC I-Class
• ACQUITY UPLC H-Class
• ACQUITY PREMIER

CAUSE

Clog in APH tubing

FIX or WORKAROUND

1. Backflush to try to remove the obstruction.
2. Replace APH. 
   • For H-Class, use part 205000730 (ACQUITY UPLC APH, SS, 12.5LG)
   • For I-Class, use part 205000894 (ACQ. I-Class APH, SS, 12.5 LG, .003 ID)
   • For ACQUITY PREMIER, use 205002234 (ACQUITY APH, MP35N, 12.5" HPS)

ADDITIONAL INFORMATION