Baseline is affecting peak shape - WKB1342
Article number: 1342
SYMPTOMS
- Peak shape not normal
(e.g.,
instead of the expected 
) - Baseline does not return to pre-peak level
- Large tailing
ENVIRONMENT
- ACQUITY UPLC
- ACQUITY UPLC H-Class
- ACQUITY UPLC I-Class
- ACQUITY UPLC TUV
- ACQUITY UPLC PDA
CAUSE
Contamination in the flow cell
FIX or WORKAROUND
Follow the Controlling Contamination cleaning procedure.
If that doesn't work , replace the flow cell .