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Baseline is affecting peak shape - WKB1342

Article number: 1342

SYMPTOMS

  • Peak shape not normal
    (e.g., bad.png instead of the expected good.png)
  • Baseline does not return to pre-peak level
  • Large tailing

ENVIRONMENT

  • ACQUITY UPLC
  • ACQUITY UPLC H-Class
  • ACQUITY UPLC I-Class
  • ACQUITY UPLC TUV
  • ACQUITY UPLC PDA

CAUSE

Contamination in the flow cell

FIX or WORKAROUND

Follow the Controlling Contamination cleaning procedure.

ADDITIONAL INFORMATION

Controlling Contamination in UPLC/MS and HPLC/MS Systems

 

UPAPDA, UPBINARY, UPC2PDA, UPPDA, UPPDAARC, UPPDAARCB, UPPDA-E, UPPDA-L, UPPDALTC, UPPDATC, UPPPDA, UPPTUV, UPQSM, UPQSM+, UPQSMBIO, UPQSMBIO+, UPSMFTN, UPSMFTN+, UPSMFTNB+, UPSMFTNBIO, UPSMPMGR, UPTUV, UPTUVARC, UPTUVARCB, UPTUV-E, UPTUVTC

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