Baseline is affecting peak shape - WKB1342
Article number: 1342
SYMPTOMS
- Peak shape not normal
(e.g.,
instead of the expected 
) - Baseline does not return to pre-peak level
- Large tailing
ENVIRONMENT
- ACQUITY UPLC
- ACQUITY UPLC H-Class
- ACQUITY UPLC I-Class
- ACQUITY UPLC TUV
- ACQUITY UPLC PDA
CAUSE
Contamination in the flow cell
FIX or WORKAROUND
Follow the Controlling Contamination cleaning procedure.
ADDITIONAL INFORMATION
Controlling Contamination in UPLC/MS and HPLC/MS Systems
id1342, A-30PDA, A-30UV, UPAPDA, UPARPTUV, UPBINARY, UPC2PDA, UPPDA, UPPDAARC, UPPDAARCB, UPPDA-E, UPPDA-L, UPPDALTC, UPPDATC, UPPPDA, UPPTUV, UPQSM, UPQSM+, UPQSMBIO, UPQSMBIO+, UPSMFTN, UPSMFTN+, UPSMFTNB+, UPSMFTNBIO, UPTUV, UPTUVARC, UPTUVARCB, UPTUV-E, UPTUVTC