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Waters

With ACQUITY Arc, baseline ripples during gradient - WKB108324

Article number: 108324

SYMPTOMS

  • The baseline ripples during the gradient
  • Leak test successful
  • No pressure abnormalities seen during run

ENVIRONMENT

  • ACQUITY Arc
  • 2998 Photodiode Array Detector
  • 2489 UV/Vis Detector

CAUSE

The pump stroke volume is high.

FIX or WORKAROUND

  • When using the Path 1 flow path, set the stroke volume to 132 μL (default).
  • When using the Path 2 flow path, set the stroke volume to 66 μL.

ADDITIONAL INFORMATION

id108324, 2489, 2489B, 2489SFC, 2998, 2998B, 2998SFC, A-10PDA, A-10UV, baseline noise, UPAQSM, UPARBQSM, UPARBSMFTN, UPARCH30, UPARHQSM, UPARQSM, UPARSMFTN, UPPDAARCB

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