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Can I spin down 96-well plates during GlycoWorks RFMS, instead of using positive/negative pressure? - WKB85264

Article number: 85264

ENVIRONMENT

  • HILIC
  • 96-well collection plates
  • GlycoWorks RFMS

ANSWER

Yes, you can. Centrifugation provides a consistent force that, because it ramps up slowly, usually leads to a good flow rate and complete elution. It typically forces a "complete elution" from the sorbent bed, helping to overcome losses due to lack of vacuum or pressure.

Waters recommends that you centrifuge the collection plate at 4,000 g to get a flow rate of about 30-50 μL/min.

ADDITIONAL INFORMATION

 

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