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Can I use the Porapak RXN CX for removal of TFA from my peptides? - WKB84109

Article number: 84109

ENVIRONMENT

  • Porapak
  • RXN
  • CX
  • Peptide
  • SPE
  • Solid phase extraction
  • Buffer exchange
  • TFA removal

ANSWER

You can use the Porapak RXN CX to remove TFA from peptides.  

ADDITIONAL INFORMATION

The Porapak RXN CX protocols were not optimized with peptides, so if using the protocols, keep 20% water present at each step to ensure peptide solubility.  

For more optimized protocols, see How do I desalt my peptides using offline solid phase extraction?

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