Can ion exchange mechanism of the Oasis Mixed-Mode be interfered with in presence of high salt matrix? - WKB61481
Article number: 61481
ENVIRONMENT
- Solid-phase extraction (SPE)
- Oasis Mixed Mode
- WAX
- Ion exchange
ANSWER
Yes. If the salt content is high, the ionic strength and amount of salt can interfere with the ion exchange of the ionic analytes with the surface charge.
ADDITIONAL INFORMATION
For additional information, see Can I try a different buffer and pH when doing the generic methods for Oasis Mixed Mode cartridges?
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