Can I use Oasis SPE products for extraction of intact proteins from a sample? - WKB57582

ENVIRONMENT

• Sample preparation
• Solid-phase extraction (SPE)
• Oasis cartridges
• Sep-Pak cartridges

ANSWER

No

ADDITIONAL INFORMATION

The pore size of the Oasis packings is 80 Angstrom. Intact proteins are generally too large to retain on Oasis packings because the proteins are excluded from entering the pores due to their size in solution.

See Waters AccellPlus QMA and CM Bulk Media to learn if AccellPlus packings would work for your application.

See Waters Sep-Pak Sample Extraction Products Brochure for a list of SPE cartridges packed with AccellPlus Ion Exchange Packings.