Why would I want to choose IonHance HFIP (hexafluoroisopropanol) over other brands of HFIP? - WKB297434

ENVIRONMENT

• Hexafluoroisopropanol (HFIP)
• IonHance HFIP

ANSWER

IonHance HFIP's reduced sodium and potassium content results in cleaner MS spectra.

This improves the accuracy and confidence in oligonucleotide sequence assignments.

ADDITIONAL INFORMATION

IonHance HFIP is a new source of high-purity HFIP reagent, specifically designed for ion-pairing reverse-phase (IP-RP) LC-MS oligonucleotide analysis. IonHance HFIP undergoes a proprietary distillation process, ensuring ultra-low metal content (Na <100 ppb, K <100 ppb) and minimizing MS adduct formation. Each container holds 10 mL of reagent for mobile phase preparation.

IonHance HFIP Care & Use Manual

Application note:

Evaluating IonHance Hexafluoroisopropanol (HFIP) for Enhanced LC-MS Oligonucleotide Analysis