How do we define the pKa of an ionizable compound? - WKB65740
Article number: 65740
ENVIRONMENT
- pKa
- Ionizable compounds
- Mobile phase
- Method development
- Optimization
ANSWER
The pKa of an ionizable compound is the pH at which the compound is 50% ionized and 50% neutral.
ADDITIONAL INFORMATION
For additional information, see the Preparative Liquid Chromatography Primer.
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