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Should I wash the LC system with RNase-free water before doing oligonucleotide analysis? - WKB53373

Article number: 53373

ENVIRONMENT

  • Oligonucleotide analysis
  • Mobile phase
  • RNase-free water
  • System cleaning
  • ACQUITY UPLC
  • HPLC
  • OST

ANSWER

It is not necessary to pre-rinse the system with RNase-free water. The system should be passivated prior to use. 

ADDITIONAL INFORMATION

For additional information, see How to clean and flush the Alliance HPLC System and Acquity UPLC System to remove contamination (Cleaning conditions #3 using 30% phosphoric acid).

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