What is a good column choice for the USP monograph for sucralfate (assay), which calls for a 3.9-mm × 30-cm column that contains packing L8? - WKB57532
ENVIRONMENT
- USP
- Monograph
- Sucralfate
- uBondapak NH2
ADDITIONAL INFORMATION
This is the specific column the USP used to validate the assay for sucralfate. To find this information on the USP-NF website, select Resources, selecting Chromatographic Column, and then search for the monograph for sucralfate.
A possible alternate column, which can maintain the L/Dp ratio compared to the uBondapak NH2 column is:
SKU: PSS831113 - Spherisorb Amino (NH2) Column, 80Å, 5 µm, 4.6 mm X 150 mm, 1/pk
Note: Changing columns for USP monographs me result in different selectivity and/or retention times of analytes of interest.
Also see:
Future-Proof Solutions for Regulated Laboratories In the Face of Changing USP <621> Guidelines.
Chapter and Verse: USP 621 and You (blog).
Waters Spherisorb Columns Web Page
Waters Spherisorb Columns Brochure
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