Are APC XT columns compatible with 100% hexafluoroisopropanol (HFIP)? - WKB48214

ENVIRONMENT

Advanced Polymer Chromatography (APC) column.

ANSWER

Yes.

ADDITIONAL INFORMATION

Although not listed in the solvent list for APC columns, HFIP is acceptable for use on ACQUITY APC Columns.

The maximum flow rates, when using HFIP, should be the flow rates shown in the care and use manual for solvents with a viscosity of greater than 0.6 cP.

In addition, although HFIP is not listed in the care and use manual, see table 4 for common solvents run on APC columns:  

ACQUITY APC Columns Care & Use Manual

Consult with Instrument Technical Service to verify if your ACQUITY APC system or other system is compatible with HFIP before using HFIP on your system.