What is a good UPLC HILIC column choice for analysis of oligonucleotides, nucleic acids, and viral vectors such as AAVs? - WKB297436
Article number: 297436
ENVIRONMENT
- Column selection
- HILIC
- AAVs
- Oligonucleotides
- Nucleic acids
- GTxResolve
- MaxPeak Premier
- High Performance Surfaces (HPS)
ANSWER
GTxResolve Premier BEH Amide 300Å
ADDITIONAL INFORMATION
GTxResolve Premier BEH Amide 300Å columns are a double batch tested (glycoprotein + 100 mer ssDNA ladder) column line designed for out-of-the-box analysis of oligonucleotides, nucleic acids, and viral vectors such as AAVs.
Orthogonal techniques to IP-RP are a popular discussion for oligonucleotide analysts. HILIC chromatography utilizes easy-to-prepare ammonium-based buffers without the need for dedicating a system to ion pairing alkyl amine reagents.
GTxResolve Premier BEH Amide 300 Å 1.7 µm Column Care and Use Manual
Application note: