Will residual TFA bind to a reverse-phase column? - WKB247940
Article number: 247940
ENVIRONMENT
- Reverse phase
- LC-MS
- TFA
- C18
- HDX
- ACQUITY M-Class
- nanoACQUITY
ANSWER
Yes
ADDITIONAL INFORMATION
TFA mobile phase additive will stick to materials in the LC flow path, trap, and columns and can be a source of TFA adduct carryover.
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