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Waters

How much sample can I load on a 3.0 x 100 mm reverse-phase column? - WKB236864

Article number: 236864

ENVIRONMENT

  • Reverse-phase columns
  • C18
  • Mass load

ANSWER

The approximate load for a small molecule is 2.5 mg. The approximate load for a small, water soluble peptide is 0.25–0.5 mg.

ADDITIONAL INFORMATION

The mass load varies based on sample solubility in water and small molecule vs. large molecule. It is determined experimentally.

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