Does Waters have a reverse-phase UPLC, UHPLC, or HPLC method for separation of a 16 kilobase mRNA? - WKB236274
Article number: 236274
ENVIRONMENT
- mRNA (messenger RNA)
- Ribonucleic acid (RNA)
- UltraPerformance Liquid Chromatography (UPLC)
- Ultra High Performance Liquid Chromatography (UHPLC)
- High Performance Liquid Chromatography (HPLC)
- Protein-Pak
- Hi Res Q
ANSWER
No
ADDITIONAL INFORMATION
Waters has not developed a reverse-phase method for such a long oligonucleotide.
Waters has developed a dsDNA separation using a Protein-Pak Hi Res Q (strong anion exchange) column that shows as high as 10 kb:
Protein-Pak Hi Res Ion-Exchange (IEX) Columns for ACQUITY UPLC Brochure
Protein-Pak Hi Res Ion-Exchange (IEX) Columns and Standards Care & Use Manual