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Waters

How can we tell if a column will give us problems with MS bleed? - WKB232642

Article number: 232642

ENVIRONMENT

  • Method development
  • MS-column compatibility

ANSWER

Without running experiments on a number of columns, the bonding technology used for a specific brand/chemistry can be a good predictor of MS bleed:

  • Monofunctional (Not Good)
  • Difunctional (OK)
  • Trifunctional (Good)

See the wall chart under ADDITIONAL INFORMATION for a specific brand/chemistry.

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