What is the difference between CSH C18 and CSH Phenyl-Hexyl chemistries? - WKB220178
Article number: 220178
ENVIRONMENT
- Column chemistry
- CSH C18
- CSH Phenyl-Hexyl
- ACQUITY
- XSelect
ANSWER
The C18 ligand is an alkyl chain and the Phenyl is a ring structure.
The C18 is more nonpolar than the Phenyl and has more retention for a nonpolar compound.
The two chemistries can have different selectivities because the Phenyl can interact with the pi elections of aromatic ring structures.
ADDITIONAL INFORMATION
For additional information, see Method Development of Ten Antibiotic Compounds Using a Systematic Screening Protocol on an ACQUTIY Arc with UV and QDa Detection.
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