Do ESI source optimization conditions for best analyte detection and identification translate across different vendors' mass specs? - WKB95983
Article number: 95983
ENVIRONMENT
- amino acid
- ESI
- electrospray ionization
- MS
- optimization
- method development
- mass spec
- AccQ-Tag
- AccQ-Fluor
- derivatization
ANSWER
No.
ADDITIONAL INFORMATION
If the compound can ionize and be detected with a Waters MS detector, it can be ionized with another vendors' MS detector. However, the ESI source conditions to optimize for a method are not equivalent across different vendors' mass specs. Method Development conditions must be done specifically for the MS in use. Consult the vendor of the MS directly for tips on best optimization utilizing that detector.
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