Does guanidine derivatize with the AccQ•Tag reagent kit? - WKB231531
Article number: 231531
ENVIRONMENT
- AccQ•Tag
- AccQ•Tag Ultra
- AccQ•Fluor
- Derivatization
- Guanidine
ANSWER
No; the guanidine structure suggests that the derivatization may not be efficient.
ADDITIONAL INFORMATION
The resonance reduces the overall electron density at a given point in the structure. Waters has not evaluated guanidine tagged with AccQ•Tag reagent, but the structure suggests that the tag will not be efficiently reacted to produce a stable derivatized compound.
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